FETUA rabbit pAb

Function: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. polymorphism: There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256; AHSG*2 has Met-248/Ser-256. similarity: Belongs to the fetuin family. similarity: Contains 2 cystatin domains. subunit: Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. tissue specificity: Synthesized in liver and selectively concentrated in bone matrix. Secrete din plasma. It is also found in dentin in much higher quantities than other plasma proteins.

Product Specifications

Background

Function:Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions., polymorphism:There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256; AHSG*2 has Met-248/Ser-256., similarity:Belongs to the fetuin family., similarity:Contains 2 cystatin domains., subunit:Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond., tissue specificity:Synthesized in liver and selectively concentrated in bone matrix. Secrete din plasma. It is also found in dentin in much higher quantities than other plasma proteins.

UniProt

P02765

Swiss Prot

P02765

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human FETUA

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:1000-2000 ELISA 1:5000-20000

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Secreted.

Other Product Names

Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B]