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MIND4-19

MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington's disease[1].

Product Specifications

CAS Number

129544-85-0

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mind4-19.html

Purity

99.93

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C1(COC2=CC=CC=C2)=NN=C(SCC3=CC=CC=C3)N1C4=CC=CC=C4

Molecular Formula

C22H19N3OS

Molecular Weight

373.47

Precautions

H315, H319

References & Citations

[1]Quinti L, et al. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models. Cell Chem Biol. 2016 Jul 21;23 (7) :849-861.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SIRT2

Available Sizes

Frequently Asked Questions

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