OGT-IN-1

OGT-IN-1 (Compound 5) is a potent OGT inhibitor. OGT-IN-1 inhibits sOGT and ncOGT with IC50s of 27 and 10 μM, respectively[1].

Product Specifications

CAS Number

[371215-02-0]

UNSPSC

12352005

Target

OGT

Type

Reference compound

Related Pathways

Neuronal Signaling

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ogt-in-1.html

Purity

98.14

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N1C(OC2=CC=C(Cl)C=C12)=O)OC3=CC=CC=C3

Molecular Formula

C14H8ClNO4

Molecular Weight

289.67

References & Citations

[1]Gross BJ, et al. Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc. 2005 Oct 26;127 (42) :14588-9.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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