OGT-IN-1
OGT-IN-1 (Compound 5) is a potent OGT inhibitor. OGT-IN-1 inhibits sOGT and ncOGT with IC50s of 27 and 10 μM, respectively[1].
Product Specifications
CAS Number
[371215-02-0]
UNSPSC
12352005
Target
OGT
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ogt-in-1.html
Purity
98.14
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N1C(OC2=CC=C(Cl)C=C12)=O)OC3=CC=CC=C3
Molecular Formula
C14H8ClNO4
Molecular Weight
289.67
References & Citations
[1]Gross BJ, et al. Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc. 2005 Oct 26;127 (42) :14588-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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