OGT-IN-1

OGT-IN-1 (Compound 5) is a potent OGT inhibitor. OGT-IN-1 inhibits sOGT and ncOGT with IC50s of 27 and 10 μM, respectively[1].

OGT

Reference compound

Neuronal Signaling

Metabolic Disease

https://www.medchemexpress.com/ogt-in-1.html

98.14

DMSO : 50 mg/mL (ultrasonic)

O=C(N1C(OC2=CC=C(Cl)C=C12)=O)OC3=CC=CC=C3

289.67

[1]Gross BJ, et al. Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc. 2005 Oct 26;127(42):14588-9.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-101548/OGT-IN-1-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-101548/OGT-IN-1-SDS-MedChemExpress.pdf

No Development Reported

371215-02-0