NA-1-157
Product Specifications
UNSPSC Description
NA-1-157 is a potent irreversible covalent inhibitor of the GES-5 carbapenemase, with a MIC of 0.5 μg/mL[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/na-1-157.html
Solubility
10 mM in DMSO
Smiles
C[C@]1([C@H]2[C@H](O)C)CC(S[C@@H]3CC(C(N(C)C)=O)NC3)=C(C(O)=O)N1C2=O
Molecular Weight
383.46
References & Citations
[1]Nichole K Stewart, et al. Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase. ACS Infect Dis. 2024 Mar 21.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161397/NA-1-157-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161397/
Clinical Information
No Development Reported
Curated Selection
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