μ-Conotoxin PIIIA
Product Specifications
CAS Number
184840-20-8
UNSPSC Description
μ-Conotoxin PIIIA is a sodium channel (NaV 1.4) blocker. μ-Conotoxin PIIIA can be isolated from Conus purpurascens[1][2].
Target Antigen
Sodium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
O=C1N2[C@@](C[C@@H](O)C2)(C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@]3(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@]4(CSSC[C@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]5NC(=O)CC5)CCCNC(=N)N)=O)CC(C)C)=O)C(=O)N[C@](C(=O)NCC(=O)N[C@H]1CC6=CC=CC=C6)(CSSC[C@](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@]8(N(C(=O)[C@H](CCCCN)NC4=O)C[C@H](O)C8)[H])(C(=O)N[C@H](C(N)=O)CSSC3)[H])[H])[H])[H])[H]
Molecular Weight
2605.06
References & Citations
[1]Tietze AA, et al. Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4. Angew Chem Int Ed Engl. 2012 Apr 23;51(17):4058-61.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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