5-trans U-44069
5-trans U-44069 is the trans isomer of the thromboxane receptor agonist U-44069. 5-trans U-44069 inhibits prostaglandin E2 synthase activity[1].
Product Specifications
CAS Number
330796-57-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PGE synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/5-trans-u-44069.html
Solubility
10 mM in DMSO
Smiles
OC(CCC/C=C/C[C@@H]1[C@H]([C@@]2([H])C[C@]1([H])OC2)/C=C/[C@@H](O)CCCCC)=O
Molecular Formula
C21H34O4
Molecular Weight
350.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Quraishi O, et al. Inhibition of inducible prostaglandin E (2) synthase by 15-deoxy-Delta (12,14) -prostaglandin J (2) and polyunsaturated fatty acids. Biochem Pharmacol. 2002 Mar 15;63 (6) :1183-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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