5-trans U-44069

5-trans U-44069 is the trans isomer of the thromboxane receptor agonist U-44069 (HY-121825) . 5-trans U-44069 inhibits prostaglandin E2 synthase activity[1].

Product Specifications

CAS Number

[330796-57-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PGE synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/5-trans-u-44069.html

Solubility

10 mM in DMSO

Smiles

OC(CCC/C=C/C[C@@H]1[C@H]([C@@]2([H])C[C@]1([H])OC2)/C=C/[C@@H](O)CCCCC)=O

Molecular Formula

C21H34O4

Molecular Weight

350.49

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Quraishi O, et al. Inhibition of inducible prostaglandin E (2) synthase by 15-deoxy-Delta (12,14) -prostaglandin J (2) and polyunsaturated fatty acids. Biochem Pharmacol. 2002 Mar 15;63 (6) :1183-9.