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Apraclonidine (hydrochloride) (Standard)

Apraclonidine (hydrochloride) (Standard) is the analytical standard of Apraclonidine (hydrochloride) . This product is intended for research and analytical applications. Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid[1][2].

Product Specifications

CAS Number

73218-79-8

Product Name Alternative

ALO 2145 (Standard)

UNSPSC

12352005

Target

Adrenergic Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/apraclonidine-hydrochloride-standard.html

Smiles

NC1=CC(Cl)=C(NC2=NCCN2)C(Cl)=C1.[H]Cl

Molecular Formula

C9H11Cl3N4

Molecular Weight

281.57

References & Citations

[1]Wijemanne S, et al. Apraclonidine in the treatment of ptosis. J Neurol Sci. 2017;376:129‐132.|[2]Searles RV, et al. Aqueous humor dynamics in anesthetized rats infused with intracameral apraclonidine. Pharmacology. 1999;58 (4) :220‐226.|[3]Yoriko Hayasaka, et al. Effects of topical antiglaucoma eye drops on prostaglandin E (2) -induced aqueous flare elevation in pigmented rabbits. Invest Ophthalmol Vis Sci

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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