(S) -NDT-19795
(S) -NDT-19795 is a potent NLRP3 inflammasome inhibitor. (S) -NDT-19795 blocks NLRP3 activation by inhibiting NLRP3 ATPase activity, thereby reducing the levels of pro-inflammatory cytokines IL-1β and IL-18. (S) -NDT-19795 can be used in the study of neurodegenerative diseases, cardiovascular diseases, metabolic diseases, and autoimmune diseases[1].
Product Specifications
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/s-ndt-19795.html
Smiles
OC([C@H](CC1=NC=CC=N1)OC(NC2=C3C(CCC3)=CC4=C2CCC4)=O)=O
Molecular Formula
C20H21N3O4
Molecular Weight
367.40
References & Citations
[1]Chen X, et al. The research progression of direct NLRP3 inhibitors to treat inflammatory disorders[J]. Cellular Immunology, 2024: 104810.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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