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Metamizole (sodium hydrate) (Standard)

Metamizole (sodium hydrate) (Standard) is the analytical standard of Metamizole (sodium hydrate) . This product is intended for research and analytical applications. Metamizole sodium hydrate (Dipyrone) is an orally active cyclooxygenase (COX) inhibitor.. Metamizole sodium hydrate can inhibit cell proliferation and promote cell apoptosis. Metamizole sodium hydrate has anti-inflammatory and antioxidant activities. Metamizole sodium hydrate is an antipyretic, analgesic and spasmolytic agent. Metamizole sodium hydrate can be used in research to relieve a variety of pain[1][2][3][4][5].

Product Specifications

CAS Number

5907-38-0

Product Name Alternative

Dipyrone (hydrate) (Standard) ; Methamizole (sodium hydrate) (Standard)

UNSPSC

12352005

Target

Apoptosis; COX; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/metamizole-sodium-hydrate-standard.html

Smiles

O=S(CN(C1=C(C)N(C)N(C2=CC=CC=C2)C1=O)C)(O[Na])=O.O

Molecular Formula

C13H18N3NaO5S

Molecular Weight

351.35

References & Citations

[1]Pierre SC, et al. Inhibition of cyclooxygenases by dipyrone. Br J Pharmacol. 2007 Jun;151 (4) :494-503.|[2]De Luna-Bertos E, et al. Therapeutic doses of nonsteroidal anti-inflammatory drugs inhibit osteosarcoma MG-63 osteoblast-like cells maturation, viability, and biomineralization potential. ScientificWorldJournal. 2013 Sep 19;2013:809891.|[3]Malsy M, et al. Effects of metamizole, MAA, and paracetamol on proliferation, apoptosis, and necrosis in the pancreatic cancer cell lines PaTu 8988 t and Panc-1. BMC Pharmacol Toxicol. 2017 Dec 6;18 (1) :77.|[4]Zajaczkowska R, et al. Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain. Pharmacol Rep. 2020 Oct;72 (5) :1310-1322.|[5]Ince I, Aksoy M, et al. A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats. J Invest Surg. 2015 Jun;28 (3) :173-80.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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