Fumonisin B2-13C34

Fumonisin B2-13C34 is the 13C labeled Fumonisin B2 (HY-N6723) [1]. Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis[2][3].

Product Specifications

CAS Number

[1217481-36-1]

UNSPSC

12352211

Hazard Statement

H225-H302-H319

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fumonisin-b2-13c34.html

Concentration

13.52 μM * 1.2 mL in Acetonitrile

Solubility

10 mM in DMSO

Smiles

O[13C]([13CH2][13C@@H]([13C](O)=O)[13CH2][13C](O[13C@@H]([13CH2][13C@@H]([13CH3])[13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13C@@H](O)[13CH2][13C@H](O)[13C@@H](N)[13CH3])[13C@@H]([13C@H]([13CH3])[13CH2][13CH2][13CH2][13CH3])O[13C]([13CH2][13C@H]([13C](O)=O)[13CH2][13C](O)=O)=O)=O)=O

Molecular Formula

13C34H59NO14

Molecular Weight

739.58

Precautions

P210-P233-P240-P241-P242-P243-P264-P270-P280-P303+P361+P353-P305+P351+P338-P330-P370+P378-P403+P235-P501

References & Citations

[1]Henry MH, et al. The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poult Sci. 2001 Apr;80 (4) :401-7.|[2]Wei T, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013;6 (4) :270-4.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-220.