Human Complement Factor B Deficient Serum

<strong>Human Complement Factor B Deficient Serum</strong>_x000D_ <strong>Catalog number:</strong> B2015464_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Serum_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Complement Factor, C3/C5 Convertase, CFB, GBG, Glycine-rich Beta Glycoprotein, PBF2, Properdin Factor B_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Zanchi C, Locatelli M, Corna D, Cerullo D, Fishilevich E, Desai D, Rottoli D, Donadelli R, Noris M, Zoja C, Remuzzi G, Benigni A. Liver factor B silencing to cure C3 glomerulopathy: Evidence from a mouse model of complement dysregulation Mol Immunol. 2023 Sep;161:25-32._x000D_ 2: Bitencourt CS, Duarte CG, Azzolini AE, Assis-Pandochi AI. Alternative complement pathway and factor B activities in rats with altered blood levels of thyroid hormone Braz J Med Biol Res. 2012 Mar;45(3):216-21._x000D_ 3: Udsen M, Tagmose C, Garred P, Nissen MH, Faber C. Complement activation by RPE cells preexposed to TNFα and IFNγ Exp Eye Res. 2022 May;218:108982._x000D_ 4: Cao W, Pham HP, Williams LA, McDaniel J, Siniard RC, Lorenz RG, Marques MB, Zheng XL. Human neutrophil peptides and complement factor Bb in pathogenesis of acquired thrombotic thrombocytopenic purpura Haematologica. 2016 Nov;101(11):1319-1326._x000D_ 5: Ries JI, Heß M, Nouri N, Wichelhaus TA, Göttig S, Falcone FH, Kraiczy P. CipA mediates complement resistance of Acinetobacter baumannii by formation of a factor I-dependent quadripartite assemblage Front Immunol. 2022 Jul 26;13:942482._x000D_ 6: Oglesby TJ, Ueda A, Volanakis JE. Radioassays for quantitation of intact complement proteins C2 and B in human serum J Immunol Methods. 1988 May 25;110(1):55-62._x000D_ 7: Levy O, Jean-Jacques RM, Cywes C, Sisson RB, Zarember KA, Godowski PJ, Christianson JL, Guttormsen HK, Carroll MC, Nicholson-Weller A, Wessels MR. Critical role of the complement system in group B streptococcus-induced tumor necrosis factor alpha release Infect Immun. 2003 Nov;71(11):6344-53._x000D_ 8: Gupta P, Tripathy AS. Alternative pathway of complement activation has a beneficial role against Chandipura virus infection Med Microbiol Immunol. 2020 Apr;209(2):109-124._x000D_ 9: Holers VM. Phenotypes of complement knockouts Immunopharmacology. 2000 Aug;49(1-2):125-31._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/107255">10: Wilson MR, Arroyave CM, Tan EM. Activation of the alternative pathway of complement by antiserum to factor B J Lab Clin Med. 1979 Mar;93(3):493-8.</a>_x000D_ _x000D_ <strong>Products Related to Human Complement Factor B Deficient Serum can be found at</strong> <a href="https://moleculardepot.com/product-category/Biofluids/"> Biofluids</a>