ω-Conotoxin MVIIC (TFA)

ω-Conotoxin MVIIC TFA is a N- and P/Q-type Ca2+ channel blocker, significantly suppresses the 11-keto-βboswellic acid-mediated inhibition of glutamate release[1].

O=C1[C@@]2([H])N(C([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@H](CSSC[C@@]3([H])C(NC(C(NCC(NC(C(N[C@@]4([H])CSSC[C@](C(N[C@H](C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@H](C(NC(CSSC[C@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC4=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)=O)CCCCN)=O)C(N)=O)([H])C(N3)=O)=O)CC(O)=O)=O)CC5=CC=C(C=C5)O)=O)CCSC)=O)([H])[C@H](O)C)=O)CCCCN)=O)CCCNC(N)=N)=O)([H])N1)=O)CO)=O)=O)CO)=O)N)=O)CCCCN)=O)=O)CCCCN)=O)=O)C)=O)CCC2.O=C(O)C(F)(F)F

[1]Cheng Wei Lu, et al. 11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus. Planta Med. 2020 Apr;86(6):434-441.