Lipoxygenin
Lipoxygenin is a non-redox 5-lipoxygenase (5-LO) inhibitor with an IC50 of 5 μM. Lipoxygenin modulates the β-catenin-5-LO complex, inducing a decrease in β-catenin and 5-LO levels in the nucleus[1].
Product Specifications
CAS Number
2247911-68-6
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lipoxygenin.html
Smiles
OC(C1=C(OC)N=CC(C2=CC=CN=C2OC)=C1OC)C3=CC4=C(C=CC=C4)C=C3
Molecular Formula
C24H22N2O4
Molecular Weight
402.44
References & Citations
[1]Brand S, et al. Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Cell Chem Biol. 2018 Sep 20;25 (9) :1095-1106.e23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-LOX
Available Sizes
Frequently Asked Questions
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