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ML307

ML307 is a potent, sub-micromolar, first-in-class Ubc13 enzyme activity inhibitor with an IC50 of 781 nM. ML307 has the potential for immunomodulation and inflammation research[1].

Product Specifications

CAS Number

3058650-52-2

UNSPSC

12352005

Target

E1/E2/E3 Enzyme

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ml307.html

Purity

99.10

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NCC1CCN(CC2=CC(Cl)=CC=C2)CC1)[C@@H]3CCCN(C4=NC=NC5=C4N=C6CCCCN65)C3

Molecular Formula

C28H36ClN7O

Molecular Weight

522.08

References & Citations

[1]Robert Ardecky, et al. Selective UBC 13 Inhibitors. Bethesda (MD) : National Center for Biotechnology Information (US) ; 2010.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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