Iodothiouracil
Iodothiouracil exhibits high selectivity for melanoma, remains stable in the melanin in melanoma cells, and localizes remote secondary metastases of melanoma. Iodothiouracil can be used for melanoma imaging when labeled with iodine-123, and can be used for radiation therapy when labeled with iodine-131[1].
Product Specifications
CAS Number
[5984-97-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iodothiouracil.html
Smiles
O=C1NC(NC=C1I)=S
Molecular Formula
C4H3IN2OS
Molecular Weight
254.05
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Coderre JA, et al., Iodothiouracil as a melanoma localizing agent. J Nucl Med. 1986 Jul;27 (7) :1157-64.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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