Metaproterenol-d7-1 (hemisulfate)
Metaproterenol-d7-1 (hemisulfate) is deuterium labeled Metaproterenol (hemisulfate) . Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity[1][2].
Product Specifications
UNSPSC
12352005
Target
Adrenergic Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology; Cardiovascular Disease; Endocrinology
Smiles
OC1=CC(C(CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])O)=CC(O)=C1.O=S(O)(O)=O
Molecular Formula
C11H12D7NO7S
Molecular Weight
316.38
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Noh H, et al. Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications. Kidney Int. 2017 Jul;92 (1) :101-113.|[3]Ibrahim FA, et al. Highly sensitive spectrofluorimetric method for rapid determination of orciprenaline in biological fluids and pharmaceuticals. Luminescence. 2019 Feb;34 (1) :77-83.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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