LAG-3 cyclic peptide inhibitor C25
Selected Variant
HY-P10835
Size: 1 Each
LAG-3 cyclic peptide inhibitor C25 is a LAG-3 inhibitor. LAG-3 cyclic peptide inhibitor C25 has a high affinity with human LAG-3 protein with a Kd value of 0.66 μM. LAG-3 cyclic peptide inhibitor C25 can block the interaction of LAG-3 with HLA-DR (MHC-II) and activate CD8+ T cells. LAG-3 cyclic peptide inhibitor C25 can be used in the study of cancer[1].
Product Specifications
UNSPSC
12352209
Target
LAG-3
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CCSC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCCNC(N)=N)C(N[C@H]3C)=O)=O)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(O)=O)NC3=O)N
Molecular Formula
C43H68N12O12S3
Molecular Weight
1041.27
References & Citations
[1]Zhai W, et al. A novel cyclic peptide targeting LAG-3 for cancer immunotherapy by activating antigen-specific CD8+ T cell responses. Acta Pharm Sin B. 2020 Jun;10 (6) :1047-1060.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A02295-carrier-free 100 µg/Vial
Anti-UBE2I UBC9 Antibody Picoband®, Carrier-free
Sign In for Pricing
View Details 
BNC042256-100 1x 100 µL
Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker) (CPTC-AKR1B1-3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401236-100 1x 100 µL
PTH (Parathyroid Hormone) (N & C Terminal) (3H9 + PTH/1175), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040177-100 1x 100 µL
CD50 (ICAM-3) (101-1D2), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
PA1374-Cy3 100 µg/Vial
Anti-Insulin-like growth factor I IGF1 Antibody Picoband®, Cy3 Conjugate
Sign In for Pricing
View Details