REV 2871
REV 2871 (Eclazolast; CHBZ) is a potent and oral activity antiallergic agent. REV 2871 also is an irreversibility histamine release (HR) inhibitor[1][2].
Product Specifications
CAS Number
80263-73-6
Product Name Alternative
Eclazolast; CHBZ
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rev-2871.html
Solubility
10 mM in DMSO
Smiles
CCOCCOC(C1=NC(C=C(Cl)C=C2)=C2O1)=O
Molecular Formula
C12H12ClNO4
Molecular Weight
269.68
References & Citations
[1]Coutts SM, et al. REV 2871 (CHBZ) : a potent antiallergic agent with a novel mechanism of action. II. Studies on the mechanism of action. Biochem Pharmacol. 1987 Mar 1;36 (5) :673-82. |[2]Khandwala A, et al. REV 2871 (CHBZ) : a potent antiallergic agent with a novel mechanism of action. I. Activity profile as an inhibitor of mediator release. Biochem Pharmacol. 1987 Mar 1;36 (5) :663-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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