Vibecotamab
Product Specifications
UNSPSC Description
Vibecotamab (XmAb14045) is a potent bispecific antibody against CD123 and CD3 that stimulates T cell-mediated targeted killing of CD123-expressing cells. Vibecotamab has antitumor activity and can be used in acute myeloid leukaemia studies[1].
Target Antigen
CD3
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vibecotamab.html
Purity
99.34
Solubility
10 mM in DMSO
Smiles
[Vibecotamab]
References & Citations
[1]FarhadRavandiMBBS, et al. Complete Responses in Relapsed/Refractory Acute Myeloid Leukemia (AML) Patients on a Weekly Dosing Schedule of Vibecotamab (XmAb14045), a CD123 x CD3 T Cell-Engaging Bispecific Antibody; Initial Results of a Phase 1 Study. Blood, Volume 136, Supplement 1, 5 November 2020, Pages 4-5
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99521/Vibecotamab-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99521/Vibecotamab-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
2138442-13-2
Available Sizes
Curated Selection
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