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Uric acid-13C,15N3

Uric acid-13C,15N3 is the 13C-labeled and 15N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[1][2].

Product Specifications

CAS Number

2421217-23-2

UNSPSC

12352005

Target

Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/uric-acid-13c-15n3.html

Purity

99.20

Solubility

1 M NaOH : 8.33mg/mL (ultrasonic; warming; adjust pH to 12 with 1M NaOH; heat to 60°C) |10 mM in DMSO|DMSO : 0.67mg/mL (ultrasonic) |H2O : 6.25mg/mL (ultrasonic; adjust pH to 10 with 1M NaOH)

Smiles

O=C1C2=C([15NH][13C]([15NH]1)=O)NC([15NH]2)=O

Molecular Formula

C4 13CH4N 15N3O3

Molecular Weight

172.08

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 2020;50 (4) :359-375.|[3]Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32 (11) :1839-1845.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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