Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

HDAC8-IN-10

HDAC8-IN-10 (compound 15) is a potent inhibitor of HDAC8, with the IC50 of 7.6 nM. HDAC8-IN-10 is a HDAC8 target protein ligand that can be used to synthesize PROTAC YX862.

Product Specifications

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac8-in-10.html

Smiles

CCCCCCNNC(C(C=C1)=CC=C1N2CCN(C)CC2)=O

Molecular Formula

C18H30N4O

Molecular Weight

318.46

References & Citations

[1]Yufeng Xiao, et al. Discovery of a Highly Potent and Selective HDAC8 Degrader: Advancing the Functional Understanding and Therapeutic Potential of HDAC8. J Med Chem. 2024 Jul 1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC8

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human ARGLU1 activation kit by CRISPRa
GA110501 1 Kit

Human ARGLU1 activation kit by CRISPRa

Sign In for Pricing
View Details
TRAcP (Tartrate-Resistant Acid Phosphatase) (Hairy Cell Leukemia Marker) (ACP5/2336R), CF594 conjugate, 0.1mg/mL
BNC942336-100 1x 100 µL

TRAcP (Tartrate-Resistant Acid Phosphatase) (Hairy Cell Leukemia Marker) (ACP5/2336R), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Cytokeratin, LMW (KRTL/1077), CF594 conjugate, 0.1mg/mL
BNC941077-100 1x 100 µL

Cytokeratin, LMW (KRTL/1077), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
BCAT1 (NM_001178094) Human Over-expression Lysate
LC432972 20 µg

BCAT1 (NM_001178094) Human Over-expression Lysate

Sign In for Pricing
View Details
ZSWIM6 (C-term) Rabbit Polyclonal Antibody
AP54741PU-N 400 µL

ZSWIM6 (C-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
RDH14 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4G8]
TA502365AM 100 µL

RDH14 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4G8]

Sign In for Pricing
View Details