P-gp inhibitor 26
P-gp inhibitor 26 (Compound 7i) is a potent P-gp inhibitor. P-gp inhibitor 26 potently reverses P-gp-mediated multidrug resistance in K562/A02 cells[1].
Product Specifications
CAS Number
[3055666-79-7]
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p-gp-inhibitor-26.html
Smiles
O=C(NC1=CC=CC=C1/N=N/C2=CC=C(CCN3CC4=C(C=C(OC)C(OC)=C4)CC3)C=C2)C5=CC=CC=C5OC
Molecular Formula
C33H34N4O4
Molecular Weight
550.65
References & Citations
[1]Zeng M, et al. Discovery of novel third generation P-glycoprotein inhibitors bearing an azo moiety with MDR-reversing effect. Eur J Med Chem. 2024 Oct 5;280:116943.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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