P-gp inhibitor 26

P-gp inhibitor 26 (Compound 7i) is a potent P-gp inhibitor. P-gp inhibitor 26 potently reverses P-gp-mediated multidrug resistance in K562/A02 cells[1].

Product Specifications

CAS Number

[3055666-79-7]

UNSPSC

12352005

Target

P-glycoprotein

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/p-gp-inhibitor-26.html

Smiles

O=C(NC1=CC=CC=C1/N=N/C2=CC=C(CCN3CC4=C(C=C(OC)C(OC)=C4)CC3)C=C2)C5=CC=CC=C5OC

Molecular Formula

C33H34N4O4

Molecular Weight

550.65

References & Citations

[1]Zeng M, et al. Discovery of novel third generation P-glycoprotein inhibitors bearing an azo moiety with MDR-reversing effect. Eur J Med Chem. 2024 Oct 5;280:116943.