Hygromycin B (Standard)

Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

Product Specifications

CAS Number

[31282-04-9]

Product Name Alternative

Hygrovetine (Standard)

UNSPSC

12352005

Hazard Statement

H300+H310+H330

Target

Antibiotic; Bacterial; Fungal; Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hygromycin-b-standard.html

Purity

99.85

Smiles

O[C@H]([C@H]1O)C2(O[C@@]([C@@H](N)CO)([H])[C@@H]1O)O[C@@]([C@@H](O[C@@H]3CO)O[C@@]([C@H]([C@H](N)C4)O)([H])[C@@H]([C@H]4NC)O)([H])[C@@]([C@H]3O)([H])O2

Molecular Formula

C20H37N3O13

Molecular Weight

527.52

Precautions

H300+H310+H330

References & Citations

[1]Pardo JM, et al. Biochemical basis of resistance to hygromycin B in Streptomyces hygroscopicus--the producing organism. J Gen Microbiol. 1985 Jun;131 (6) :1289-98.|[2]González A, et al. Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes. Biochim Biophys Acta. 1978 Dec 21;521 (2) :459-69.|[3]Pfister P, et al. Role of 16S rRNA Helix 44 in Ribosomal Resistance to Hygromycin B. Antimicrob Agents Chemother. 2003 May;47 (5) :1496-502.