Tirandamycin A

Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties[1][2].

Product Specifications

CAS Number

[34429-70-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic; Bacterial; DNA/RNA Synthesis; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tirandamycin-a.html

Solubility

10 mM in DMSO

Smiles

O=C(/C1=C(O)\C=C\C(C)=C\[C@H]([C@@H]2[C@@H](C)[C@@]3([H])C([C@]4([H])O[C@]4(C)[C@@](O3)(C)O2)=O)C)NCC1=O

Molecular Formula

C22H27NO7

Molecular Weight

417.45

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Avelina Espinosa, et al. Antiamoebic properties of the actinomycete metabolites echinomycin A and tirandamycin A. Parasitol Res. 2012 Dec;111 (6) :2473-7.|[2]H Hagenmaier, et al. Metabiolic products of microorganisms. Tirandamycin B (author's transl) . Arch Microbiol. 1976 Aug;109 (1-2) :65-74.