InhA-IN-7
InhA-IN-7 (Compound 11) is a Triclocan derivative with inhibitory activity towards enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. InhA-IN-7 inhibits proliferations of Mycobacterium tuberculosis wildtype and mutant strains with MICs ranging from 19 to 75 μM[1].
Product Specifications
CAS Number
952588-17-9
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/inha-in-7.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C(Cl)=C1)OC2=CC=C(CCC(C)C)C=C2O
Molecular Formula
C17H18Cl2O2
Molecular Weight
325.23
References & Citations
[1]Freundlich JS, et al., Triclosan derivatives: towards potent inhibitors of drug-sensitive and drug-resistant Mycobacterium tuberculosis. ChemMedChem. 2009 Feb;4 (2) :241-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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