Nivalenol-13C15
Product Specifications
UNSPSC Description
Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801)[1]. Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product[2]. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect[3].
Target Antigen
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nivalenol-13c15.html
Solubility
10 mM in DMSO
Smiles
[13CH3][13C@@]12[13C@@]3([13C@]([H])(O[13C@]4([13C@]2([13CH2]O)[13C@H](O)[13C]([13C]([13CH3])=[13CH]4)=O)[H])[13C@H](O)[13C@H]1O)[13CH2]O3
Molecular Weight
327.20
References & Citations
[1]Bryła M, et al. Natural Occurrence of Nivalenol, Deoxynivalenol, and Deoxynivalenol-3-Glucoside in Polish Winter Wheat. Toxins (Basel). 2018 Feb 13;10(2).|[2]Aupanun S, et al. Individual and combined mycotoxins deoxynivalenol, nivalenol, and fusarenon-X induced apoptosis in lymphoid tissues of mice after oral exposure. Toxicon. 2019 Jul;165:83-94.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N6801S/Nivalenol-13C15-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N6801S/
Clinical Information
No Development Reported
CAS Number
911392-40-0
Curated Selection
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