Lucerastat
Lucerastat, the galactose form of Miglustat, is an orally-available inhibitor of glucosylceramide synthase (GCS) . Lucerastat has the potential for Fabry disease study[1][2].
Product Specifications
CAS Number
[141206-42-0]
Product Name Alternative
NB-DGJ; N- (n-Butyl) deoxygalactonojirimycin
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Glucosylceramide Synthase (GCS)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lucerastat.html
Purity
98.0
Solubility
DMSO : 22 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 24 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O[C@H]1[C@@H](CO)N(CCCC)C[C@H](O)[C@H]1O
Molecular Formula
C10H21NO4
Molecular Weight
219.28
Precautions
H315, H319
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106392/Lucerastat-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106392/Lucerastat-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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