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Mesoporphyrin IX (dihydrochloride)

Mesoporphyrin IX (dihydrochloride) is a photosensitizer that can be used to modify liposomes. Mesoporphyrin IX (dihydrochloride) can insert into lipid vesicles and disrupt the viral membrane structure in vesicular stomatitis virus (VSV), inducing cross-linking of VSV glycoproteins, thereby inhibiting viral activity[1].

Product Specifications

CAS Number

[68938-72-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

VSV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mesoporphyrin-ix-dihydrochloride.html

Purity

95.90

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(CCC1=C(C)C2=N/C1=C\C3=C(CCC(O)=O)C(C)=C(N3)/C=C(C(CC)=C4C)\N=C4/C=C(C(CC)=C/5C)\NC5=C/2)O.Cl.Cl

Molecular Formula

C34H40Cl2N4O4

Molecular Weight

639.61

Precautions

H302, H315, H319, H335

References & Citations

[1]Cruz-Oliveira C, et al. Mechanisms of Vesicular Stomatitis Virus Inactivation by Protoporphyrin IX, Zinc-Protoporphyrin IX, and Mesoporphyrin IX. Antimicrob Agents Chemother. 2017 May 24;61 (6) :e00053-17.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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