Mal-PEG8-Val-Ala-PAB-Exatecan
Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research[1].
Product Specifications
CAS Number
[2679821-39-5]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg8-val-ala-pab-exatecan.html
Purity
99.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
Molecular Formula
C66H85FN8O20
Molecular Weight
1329.42
References & Citations
[1]Manel KRAIEM. Treatment of cancer. WO2021151984A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Dictyostelium citrinum NADH-ubiquinone oxidoreductase chain 4L (nad4L)
Recombinant Dictyostelium citrinum NADH-ubiquinone oxidoreductase chain 4L (nad4L)
Recombinant Dictyostelium citrinum NADH-ubiquinone oxidoreductase chain 4L (nad4L)