Relaxin-2 (Human)

<strong>Relaxin-2 (Human)</strong> <strong>Catalog number:</strong> MDP0858 <strong>CAS Number: </strong>332837-02-2 <strong>Sequence: </strong>A-chain: Pyr-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys B-chain: Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser (Disulfide bonds between CysA10-CysA15, CysA11-CysB11, and CysA24-CysB23) <strong>Amount:</strong> 50 ug <strong>Molecular Weight:</strong> 5962.8 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Stewart DR. Commercial immunoassays for human relaxin-2 Mol Cell Endocrinol. 2019 May 1;487:94-97. 2: Nair VB, Samuel CS, Separovic F, Hossain MA, Wade JD. Human relaxin-2: historical perspectives and role in cancer biology Amino Acids. 2012 Sep;43(3):1131-40. 3: Yang M, Li J, Gu P, Fan X. The application of nanoparticles in cancer immunotherapy: Targeting tumor microenvironment Bioact Mater. 2020 Dec 26;6(7):1973-1987. 4: Hossain MA, Wade JD. The roles of the A- and B-chains of human relaxin-2 and -3 on their biological activity Curr Protein Pept Sci. 2010 Dec;11(8):719-24. 5: Lee KC, Hsieh YC, Chan CC, Sun HJ, Huang YH, Hou MC, Lin HC. Human relaxin-2 attenuates hepatic steatosis and fibrosis in mice with non-alcoholic fatty liver disease Lab Invest. 2019 Jul;99(8):1203-1216. 6: Dschietzig TB. Recombinant human relaxin-2: (how) can a pregnancy hormone save lives in acute heart failure? Am J Cardiovasc Drugs. 2014 Oct;14(5):343-55. 7: Kwok WH, Choi TLS, Leung GNW, Wong ASY, Yue SK, Wan TSM, Ho ENM. Administration study of recombinant human relaxin-2 in horse for doping control purpose Drug Test Anal. 2020 Mar;12(3):361-370. 8: Sun J, Hao W, Fillmore N, Ma H, Springer D, Yu ZX, Sadowska A, Garcia A, Chen R, Muniz-Medina V, Rosenthal K, Lin J, Kuruvilla D, Osbourn J, Karathanasis SK, Walker J, Murphy E. Human Relaxin-2 Fusion Protein Treatment Prevents and Reverses Isoproterenol-Induced Hypertrophy and Fibrosis in Mouse Heart J Am Heart Assoc. 2019 Dec 17;8(24):e013465. 9: Ma J, Niu M, Yang W, Zang L, Xi Y. Role of relaxin-2 in human primary osteosarcoma Cancer Cell Int. 2013 Jun 10;13(1):59. <a href="https://pubmed.ncbi.nlm.nih.gov/31125285">10: Wolf VL, Phillips TL, Taylor EB, Sasser JM, Ryan MJ. Human recombinant relaxin-2 does not attenuate hypertension or renal injury but exacerbates vascular dysfunction in a female mouse model of SLE Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H234-H242. </a> <br><strong>Products Related to Relaxin-2 (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>