Anti-SERPINB10 Antibody

Rabbit Polyclonal Antibody specific to SERPINB10

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Bomapin, Peptidase inhibitor 10, PI-10

Gene Name

SERPINB10

NCBI Gene ID

<a href="https://www.ncbi.nlm.nih.gov/gene/?term=SERPINB10">SERPINB10</a>

UniProt

P48595

Cellular Locus

Nucleus. Cytoplasm. Note=Mostly found in the nucleus.

Host

Rabbit

Reactivity

Human

Immunogen

Peptide corresponding to aa 316-330 of human SERPINB10 protein.

Target Antigen

Serpin B10

Target

SERPINB10

Clonality

Polyclonal

Type

Antibody

Applications

Field of Research

Neuroscience

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium which is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. {PubMed:10871600, PubMed:7592909}.

Additionnal Information

Immunoblotting: use at 1:500-1:1,000 dilution. In immunoblots, a band of approximately 45 kD is detected.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Specificity

This antibody recognizes human SERPINB10 protein, a gene product that is expressed in human bone marrow cells. Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and found in blood and extracellular fluids. A subset of the serpin family, the ov-serpins, are intracellular as well.