AChE/Aβ-IN-5
AChE/Aβ-IN-5 (compound AV-2) is a bifunctional inhibitor that targets AChE and auto-induced Aβ (Amyloid-β) aggregation. AChE/Aβ-IN-5 can significantly improve scopolamine- and Aβ-induced cognitive impairment in mice[1].
Product Specifications
CAS Number
181114-32-9
UNSPSC
12352005
Target
Amyloid-β; Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-aβ-in-5.html
Solubility
10 mM in DMSO
Smiles
C1(C2=CC=CC=C2)=NC(N3CCN(CC3)CC4=CC=CC=C4)=C5C=CC=CC5=N1
Molecular Formula
C25H24N4
Molecular Weight
380.48
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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