2-Amino-6-chloropurine-9-beta-d- (2'-deoxy-3',5'-di-o-benzoyl-2'-fluoro) arabinoriboside
Selected Variant
HY-W605935
Size: 1 Each
2-Amino-6-chloropurine -9-beta-D- (2’-deoxy-3’,5’-di-O-benzoyl-2’-fluoro) arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
118373-61-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-amino-6-chloropurine-9-beta-d-2-deoxy-3-5-di-o-benzoyl-2-fluoro-arabinoriboside.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(N=C2)C(N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)=O)[C@@H](OC(C5=CC=CC=C5)=O)[C@@H]3F)=NC(N)=N1
Molecular Formula
C24H19ClFN5O5
Molecular Weight
511.89
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
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