2-MeS-ATP
2-MeS-ATP (2-Methylthio-ATP) is an analog of adenosine nucleotides and acts as a P2Y purinergic receptor agonist specific for adenosine nucleotide activation. 2-MeS-ATP is also able to inhibit the release of toxic mediators from macrophages stimulated by endotoxin (LPS) . 2-MeS-ATP can be used in the study of endotoxin shock and inflammatory diseases[1].
Product Specifications
CAS Number
43170-89-4
Product Name Alternative
2-Methylthio-ATP
UNSPSC
12352005
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology; Others
Assay Protocol
https://www.medchemexpress.com/2-mes-atp.html
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(SC)N=C3N)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O
Molecular Formula
C11H18N5O13P3S
Molecular Weight
553.27
References & Citations
[1]Proctor R A, et al. Protection of mice from endotoxic death by 2-methylthio-ATP[J]. Proceedings of the National Academy of Sciences, 1994, 91 (13) : 6017-6020.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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