Shepherdin (79-87)
Shepherdin (79-87) is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity[1].
Product Specifications
CAS Number
[861224-28-4]
UNSPSC
12352209
Target
HSP; Survivin
Type
Peptides
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shepherdin-79-87.html
Solubility
H2O
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC([C@H](CS)NC(CNC([C@H](CO)NC([C@H](CO)NC([C@H](CC2=CNC=N2)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C41H64N12O12S
Molecular Weight
949.09
References & Citations
[1]Plescia J, et al. Rational design of shepherdin, a novel anticancer agent. Cancer Cell. 2005 May;7 (5) :457-68.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
HSP90
Curated Selection
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