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Shepherdin (79-87)

Shepherdin (79-87) is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity[1].

Product Specifications

CAS Number

861224-28-4

UNSPSC

12352209

Target

HSP; Survivin

Type

Peptides

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/shepherdin-79-87.html

Solubility

H2O

Smiles

CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC([C@H](CS)NC(CNC([C@H](CO)NC([C@H](CO)NC([C@H](CC2=CNC=N2)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C41H64N12O12S

Molecular Weight

949.09

References & Citations

[1]Plescia J, et al. Rational design of shepherdin, a novel anticancer agent. Cancer Cell. 2005 May;7 (5) :457-68.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

HSP90

Frequently Asked Questions

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