Moperone
Moperone (R 1658) is an antagonist for D2 dopamine receptor and D3 dopamine receptor, with IC50 of 1.0 nM and 1.0 nM[1].
Product Specifications
CAS Number
1050-79-9
Product Name Alternative
Methylperidol; R 1658
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/moperone.html
Smiles
CC1=CC=C(C2(O)CCN(CCCC(C3=CC=C(C=C3)F)=O)CC2)C=C1
Molecular Formula
C22H26FNO2
Molecular Weight
355.45
References & Citations
[1]Burstein ES, et al., Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist. J Pharmacol Exp Ther. 2005 Dec;315 (3) :1278-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor; D3 Receptor
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR10353072 96 Well
Rat Low molecular weight phosphotyrosine protein phosphatase (ACP1) ELISA Kit
Sign In for Pricing
View Details 