Moperone
Moperone (R 1658) is an antagonist for D2 dopamine receptor and D3 dopamine receptor, with IC50 of 1.0 nM and 1.0 nM[1].
Product Specifications
CAS Number
1050-79-9
Product Name Alternative
Methylperidol; R 1658
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/moperone.html
Smiles
CC1=CC=C(C2(O)CCN(CCCC(C3=CC=C(C=C3)F)=O)CC2)C=C1
Molecular Formula
C22H26FNO2
Molecular Weight
355.45
References & Citations
[1]Burstein ES, et al., Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist. J Pharmacol Exp Ther. 2005 Dec;315 (3) :1278-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor; D3 Receptor
Available Sizes
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