Moperone

Moperone (R 1658) is an antagonist for D2 dopamine receptor and D3 dopamine receptor, with IC50 of 1.0 nM and 1.0 nM[1].

Product Specifications

CAS Number

1050-79-9

Product Name Alternative

Methylperidol; R 1658

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/moperone.html

Smiles

CC1=CC=C(C2(O)CCN(CCCC(C3=CC=C(C=C3)F)=O)CC2)C=C1

Molecular Formula

C22H26FNO2

Molecular Weight

355.45

References & Citations

[1]Burstein ES, et al., Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist. J Pharmacol Exp Ther. 2005 Dec;315 (3) :1278-87.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

D2 Receptor; D3 Receptor

Available Sizes

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