18:0 mPEG5000 PE (ammonium)
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
Product Specifications
CAS Number
[474922-77-5]
Product Name Alternative
DSPE-mPEG5000 (ammonium) ; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy (polyethylene glycol) -5000] (ammonium)
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H331, H336, H351, H361, H372
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/18-0-mpeg5000-pe-ammonium.html
Purity
99
Solubility
10 mM in DMSO
Smiles
O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O)OCCOC.N.[n]
Molecular Formula
(C2H4O) nC43H84NO10P.H3N
Molecular Weight
5000 (Average)
Precautions
H302, H315, H319, H331, H336, H351, H361, H372
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
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