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ATR kinase-IN-2

ATR kinase-IN-2 (Compound I-G-27) is a ATR protein kinase inhibitor with the Ki of 0.01 ~ 1 μΜ and can be used for study of cancer[1].

Product Specifications

CAS Number

1613196-91-0

UNSPSC

12352005

Target

ATM/ATR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PI3K/Akt/mTOR

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/atr-kinase-in-2.html

Smiles

O=C(C1=C2N=CC(F)=CN2N=C1N)NC3=C(N4CCC(CC4)C(N5CCNC(C)(C5)C)=O)C(F)=CN=C3

Molecular Formula

C24H29F2N9O2

Molecular Weight

513.54

References & Citations

[1]Nadia AHMAD, et al. Compounds useful as inhibitors of atr kinase. WO2014089379. 2015-01-15.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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