Atirmociclib
Product Specifications
CAS Number
2380321-51-5
UNSPSC Description
Atirmociclib (PF-07220060; example A94) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atirmociclib.html
Smiles
CC(N1C2=CC(C3=NC(N[C@H]4[C@@H](COCC4)O)=NC=C3Cl)=CC(F)=C2N=C1C(C)(O)C)C
Molecular Weight
463.93
References & Citations
[1]Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.
Shipping Conditions
Room Temperature
Available Sizes
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