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Atirmociclib

Product Specifications

CAS Number

2380321-51-5

UNSPSC Description

Atirmociclib (PF-07220060; example A94) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1].

Target Antigen

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/atirmociclib.html

Smiles

CC(N1C2=CC(C3=NC(N[C@H]4[C@@H](COCC4)O)=NC=C3Cl)=CC(F)=C2N=C1C(C)(O)C)C

Molecular Weight

463.93

References & Citations

[1]Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.

Shipping Conditions

Room Temperature

Available Sizes

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