NNMTi
NNMTi is a potent nicotinamide N-methyltransferase (NNMT) inhibitor (IC50=1.2 μM) and selectively binds to the NNMT substrate-binding site residues[2]. NNMTi promotes myoblast differentiation in vitro and enhances fusion and regenerative capacity of muscle stem cells (muSCs) in aged mice[1].
Product Specifications
CAS Number
[42464-96-0]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Amine N-methyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nnmti.html
Purity
99.64
Solubility
DMSO : 20.83 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 2.27 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[N+]1=C2C=CC=C(N)C2=CC=C1.[I-]
Molecular Formula
C10H11IN2
Molecular Weight
286.11
Precautions
H315, H319, H320
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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