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SNAP25 Recombinant Rabbit Monoclonal Antibody [JE45-86]

t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. When cloned and expressed in E.coli, where protein palmitoylation does not occur, Cys-85, Cys-88, Cys-90 and Cys-92 in the protein sequence readily form an iron-sulfur cluster. Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

bA416N4.2 antibody Bdr antibody CMS18 antibody dJ1068F16.2 antibody FLJ23079 antibody HGNC:11132 antibody MGC105414 antibody MGC139754 antibody Resistance to inhibitors of cholinesterase 4 homolog antibody RIC 4 antibody RIC-4 antibody RIC4 antibody SEC 9 antibody SEC9 antibody SNAP 25 antibody SNAP antibody SNAP-25 antibody SNAP-25B antibody SNAP25 antibody SNP 25 antibody SNP25 antibody SNP25_HUMAN antibody sp antibody SUP antibody Super protein antibody Synaptosomal associated 25 kDa protein antibody Synaptosomal associated protein antibody Synaptosomal associated protein 25 antibody Synaptosomal associated protein 25kDa antibody Synaptosomal-associated 25 kDa protein antibody Synaptosomal-associated protein 25 antibody Synaptosomal-associated protein antibody Synaptosomal-associated protein, 25-KD antibody

Abbreviation

Synaptosomal-associated protein 25 SNAP-25 Super protein (SUP) Synaptosomal-associated 25 kDa protein SNAP25 SNAP

Swiss Prot

P60880 Human, P60879 Mouse, P60881 Rat

Cellular Locus

Cytoplasm, perinuclear region. Cell membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human SNAP25 aa 51-150 / 206.

Isotype

IgG

Clone

JE45-86

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

SH-SY5Y cell lysate, Neuro-2a cell lysate, human brain tissue lysate, SH-SY5Y, human brain tissue, mouse brain tissue, rat brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:500-1:5,000 ;IF-Cell: 1:100 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 23 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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