Tyrosinase-IN-27
Product Specifications
UNSPSC Description
Tyrosinase-IN-27 (compound 6f) is a tyrosinase (TYR) inhibitor (IC50: 0.88 μM) that statically quenches TYR. Tyrosinase-IN-27 increases the hydrophobicity of the enzyme microenvironment by binding to TYR, reducing the content of α-helices in the enzyme and changing its secondary structure. Tyrosinase-IN-27 can be used in the food industry to effectively inhibit the browning of lotus root slices[1].
Target Antigen
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tyrosinase-in-27.html
Solubility
10 mM in DMSO
Smiles
CCCC1=CC(OC2=C1C=CC(OCC3=CC(C(O)=CO3)=O)=C2)=O
Molecular Weight
328.32
References & Citations
[1]He M, et al. Synthesis, anti-browning effect and mechanism research of kojic acid-coumarin derivatives as anti-tyrosinase inhibitors. Food Chem X. 2024 Jan 10;21:101128.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158235/Tyrosinase-IN-27-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158235/
Clinical Information
No Development Reported
CAS Number
2966803-96-1
Curated Selection
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