Sclerotiorin
Sclerotiorin is a reversible and uncompetitive inhibitor against soybean lipoxygenase-1 (LOX-1) (IC50: 4.2 μM) . Sclerotiorin also shows antioxidant activity by scavenging free radical (ED50: 0.12 μM), and nonenzymatic lipid peroxidation inhibition activity. Sclerotiorin has antifungal activity, and also inhibits platelet aggregation. Sclerotiorin can be purified from the fermented broth of Penicillium frequentans[1][2].
Product Specifications
CAS Number
549-23-5
UNSPSC
12352005
Target
Fungal; Lipoxygenase
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sclerotiorin.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@](C)(OC(C)=O)C(C2=COC(/C=C/C(C)=C/[C@@H](C)CC)=CC2=C1Cl)=O
Molecular Formula
C21H23ClO5
Molecular Weight
390.86
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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